National Sheep Industry Improvement Center

2015: Development of Ovine GM1 ganglioside for Huntington’s disease in cooperation with Dr. Steven Hersch, MGH/Harvard

Objective 1:  Optimization of ovine raw material for GM1 production

Objective 2: Pre-clinical studies in transgenic HD mice

$25,000, $50,000 Matching Funds:  The Shepherd’s Gift: GM1 for HD

2016: Comparison of meat composition of lambs affected with GM1 gangliosidosis to retail lamb in cooperation with Dr. Keith Underwood, SDSU, and Dr. Travis Hoffman, NDSU & UM.

Objective: to provide a complete compositional analysis of meat product from GM1 gangliosidosis lambs compared to normal commercially available lamb.

Specific Aim 1:  Analyze meat samples from GM1 lambs and commercial lambs for ash, moisture, protein, fat and carbohydrate content.

Specific Aim 2: Analyze GM1 lamb and normal commercially available lamb for ganglioside composition. $24,110

American Sheep Industry

American Sheep Industry


ASI Let’s Grow 2015:

Development of Ovine GM1 ganglioside for Huntington’s disease in cooperation with Dakota Lamb Growers Cooperative. Objective: to create a series of educational outreach videos to be used to build awareness of the GM1 production project among sheep producers. $8230

ASI Let’s Grow 2016

GM1 Sheep Production for Huntington’s Disease: Training Videos, Record Management, and Cooperator Communications in cooperation with Dakota Lamb Growers Cooperative. Objective: providing detailed information for cooperating sheep producers participating in the GM1 project. $8108